Because synbiotic skincare is a new technology, Chrisal has paid a lot of attention to demonstrating the safety of the products from the beginning of its development. Naturally, all products comply with the cosmetic guidelines and are registered in the mandatory European CPNP (Cosmetic Product Notification Portal) database.

All Synbio® products meet the following criteria:

1. All probiotics used to belong to ATCC safety class 1 (= highest safety)

2. The pro/prebiotics are 100% natural, not genetically modified (non-GMO)

3. The pro/prebiotics are approved for food according to the European Food Safety Agency (EFSA)  

    and the US FDA (GRAS status)

4. Passed the following official OECD safety tests:

a. OECD 403 Inhalation toxicity

b. OECD 404 Acute skin irritation/corrosion

c. OECD 405 Acute eye irritation/corrosion

d. OECD 406 Skin sensation

5. The prebiotics and probiotics meet the criteria for use in cosmetics, where the mandatory dermatological tests have been successfully performed.

6. The probiotics and prebiotics used also meet the safety criteria for the EU Ecolabel